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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef4ce5119eebd4af45b6497b567701f3f23cd9be93a9ef3a73a6997e0c8a8095' 
  AND token = '+SiPfS+AnDRb0hj//DpN1Y2D7dIQtfngWGU3j4tRdno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}