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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b8a4cda507aa5cd4139ce5233752df9ad87ef815f50f2e00d1ab585c7f33318' 
  AND token = '0F2yhotUUB4hdKcCeaH34aITnJgjVRRlbuZONhRZ86Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}