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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37e833e45d93b21e8457eec01a5a51429e62c8e77e02c16a70b3a90b1d1d76b8' 
  AND token = 'haUZwa4TVfuBkZNui+vwqBwPF1WpbDrVHyWHIXJuR2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}