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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a324639f934f38c3e9077def5cc4e9d004fd4cccf4abdec298dc9e8a4caa97b' 
  AND token = 'rjDnya1yClCX3CiF/Knm1yu+Ey2NsLOes0eKaIoV2IA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}