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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8bbe397fb08348ceb0ff1181239715ec243da7e2924fc141dd4ccd9f614e6c5' 
  AND token = 'S6mIrmkoIzi0zH0uWvsiTlwj2RSpmSX9auHJm7WoTMY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}