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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da300254f9dbd3eebef8ade8d8d107cf6630d0cc439b915d2a56774cb18256de' 
  AND token = 'f/I9+OVvH7S77x6jhLV8uql3jj1iGMkCsFcNg63AjXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}