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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cbf9558a494d3a6c43d770f370224c22a501f18c68b867607a3d78343a66f78' 
  AND token = 'Ku5HHKCRMPyyL+HIvtJ862haTXRsRQkLRlvRfZhAGe8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}