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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '221387d31d7f77597bff570fb99515092512a1d7c40168f4dc794b97900e6604' 
  AND token = 'aCXwgWySSXqO8qL4Y49UWYqZ6G4QA1T2bmT72wcu45g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}