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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a1776780e9032341991334608c0bc7c2f5655efae0555bb40a49574b2fcefec' 
  AND token = 'vX3igTFCIk9C+QMN4OAsA5VFFxhTFI2B+0gQn2BnIus=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}