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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6bf294614fd408f15f991be8ece675d942c10fddf7326578fcc5dc7fa75ee346' 
  AND token = 'f+Uu6T+xbQkBzGIKRWI2DKfx/DBVkiymjWucyoAKPy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}