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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bffb30b1226c3d2ef381358417d11b67f40ac9e48080af859d3b66c5f8298bff' 
  AND token = '+DKz14hvOHgRenMeoLs2VCTREiTCK5TtYIQ997cyzIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}