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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5482f6bf27b89d0ed7bbc7d7c14701bcde3a2776a3a0e994d01e2b4dd0ddbcd8' 
  AND token = 'TF1LS+9PnoXbtb/P7reGRUdf5yytSmZMJ4dIOLfInr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}