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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d2e5a52c9831301d1ce70ccf802da7919c3d09d5f64b285e72de261f83e83b8' 
  AND token = 'PziD5V0mH7qBajp+nqtw4nNCCKH0aSk6Uq77SNqJPCI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}