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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d50853b8201098d61fba5a8cad3d15aaa0434a25b86969ea9790aa631d607c0' 
  AND token = 'zI6ho0ksLVx+PI7i70t0hJZ6I8nrJx79n+mMxPXHqpE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}