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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a4243da3a281449c7f86f4c631c3c22c19ba26626722543792d96a0ee66f674' 
  AND token = 'N2td0o5EB/nPoTJozfIcNEL/EWXtFE9PeigAMYhS6VU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}