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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2681e13b9cbd67d68b291a37a624fd6c614ffaa441069f8261c9e903c86dfb56' 
  AND token = 'abgDHfnfhUcg0qR0mVR56+NzMTeEdtmEGwlBmA9gqy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}