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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16a2c5217c3fa6d23b9d881cac7c9011f792bc2bdd2eb966959685f1becd1b34' 
  AND token = 'Yr5cVQ0kykicYYTqo8mToK7t/gkg+4FtKaQ7mKUr79E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}