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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b5617184fd1a93ff1d96e9cb49c571435d778d963212993e1ac69b8b148607' 
  AND token = 'qDVPjik7CSLDx2JqLDbrgkOD5jBDafeNZiH3HZAikBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}