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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eff21f7438bd750963ab21b60263dabebe427b3e77df1250444b97c0491a7dc2' 
  AND token = '/Bxxd90IZZgV6LOxz/gll8uuAE8Pe08WgJaz0FkIBeE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}