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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e509ad1fa6a2dc1e269f66d23b913ff4c5257ff5616de3c8d641a75618270a40' 
  AND token = 'BPWEWoAl8TauRwr9bmXTT6ORUUNeNkTl+ted7FMwk1g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}