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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '755af73b1eb86f38ec46dbe373607bc3e8bff1b9442d062557b3ab614920a13b' 
  AND token = '6yORCpPmtm6Uk7ZvUV6DzZor4F1YU7mHEgjBVunui6c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}