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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd226e01ae820ef22cb29d5b9b1d9094f4d17fc1042ee444a086eec5ab17b12a1' 
  AND token = '6cweKKeU4P+jk/eJm9gBNEmbB0FDlEt6Ekx1g6fe46Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}