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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4f2767a72f979b8530e1ca7c90e7c3ce180bb7f5a89312e2a6905f63199c4f4' 
  AND token = 'sWFfb0DNwaMFuGYam1c7QirlPNn24DyCMJxd4k7yXWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}