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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b314fd34e71d626f2d6fd7659f2cc06964cc6630d44bb27974f31e478388e829' 
  AND token = 'sere5nQDA0WcBh4EvauNn/I11J79QTU47JB/wc6tdMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}