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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd4b9fa04891ba91fb59e8aeaaf403c9d2bcb52b226a1a6871d134fe3cd701cc' 
  AND token = 'dV6pxCoxFwkyur9TZ1CDt2iHMA6iuY/b8yeFiyTorP4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}