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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c438f4a7b39800f8540b6d2aba8c844cfdce86380bd53cac7093ae18ba880e1a' 
  AND token = 'UfqTy5HXMAJyca+klXWjW6MQYfMUkiHQnnOdIpWNF4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}