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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e62182f584c618fadd2de40c278a8a8a76ca8e61afb9f7099e84deb08c25472d' 
  AND token = 'istiqDX9ZZpzivQcGq7HqGF7MpkpvnoeLZ/ZFlY8YyQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}