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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e73822644fd2b01b51f9e8ac07ef58a6f447a235819dd322775a678064eac6d4' 
  AND token = 'AexAHGORpaPinmzOwz1XF/lm0ruSZcrkxjLwDHF6B5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}