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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52a681113847d2378b0c1a9da0d2baff38fae97dd2a80332f81e6ce37a27d12c' 
  AND token = 'o5vEyosHAKQsb5uCS1tLgbYEPl023I3uGs4rry4gxDs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}