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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e4087bb5bc3a1e2db3f145b4d27d7de76591d8272f5c688fbd2eaec33aab4def' 
  AND token = 'dJCS42vRg9KuW4L8YiyS+APzOPGbYMtl3eI1SoCJiD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}