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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ddbd61dcbfe7724d52d4205030e5363ee77e918a2c8563895e2aa2542aeb7ec' 
  AND token = 'AWbVVdHuZ3rXJMZQgbkbyyIAkhe4HwP93FYzeASzVlE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}