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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc496cf4eacf8cb554c8a6a9b5770c3b11b55a8c7fa7b635a0416d6bda54c04' 
  AND token = 'MebUT/CvnCORVjZJ67vRPI5I6iSYjFRSLUFWRQowgaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}