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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b4ad578b5830e28fa383aa27dc04e75f950720b697ef91708581b68d66a27b5' 
  AND token = 'm/FdRb9aN9wOyeP4zYTyk/DgJZlYOg9ujTq6tX5XlAM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}