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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3c64305deeb878a1d52106025d778e3394d7ececaa1094b6c0ec0991c697e52' 
  AND token = 'D4z0FaW1Ctwejg171SAKQqH0be/wmt4vSk9W9qYtoOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}