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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c934812071fee9f519d140bbbeaac920c1c3b86ee328df6e2c78648217c3a473' 
  AND token = 'KRSDWtDl78eyT35Jd7F1Yc1noP0iHzcXTNa77Z2qzS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}