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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f5de86b5898c334c356256657bda6bb37afe2905fa6c3b05a4aa58127090da8' 
  AND token = 'qe5fy5EowFrJHy+/C50i2+vN2MRb8RGItM1QxlSrLl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}