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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1012a8df42abf0656880077e3d63eb95c945b807a1f0ea4dfa9a4ae62e762a76' 
  AND token = 'MY+dnBID/B1xGVoK1QItc98lbId0Ymp7HdXgFVP01l8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}