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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fca4a17d4f857e0b8f87704216e861c17d19cb7a7cb1f4ec6353db479bab9b46' 
  AND token = 'qc5SaLB9JVhIlNvKoVR9UxUwjoTKCNOyCoW84HDbWmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}