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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51c71628f5df02ad1fe00887f66c8680f7d6396ddf7988d47bdf2b71a6b0b841' 
  AND token = 'kJ1LY33vjtm4IQ8s5NS79zGcNkz9ClWPks11fgjMml4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}