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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '459cd0ec3131610fb030c3382c42b74f9fb6a75db02d8ed5f2f96057c57f2f06' 
  AND token = '+2Sfsw7O05Ku36E428tHXh7vQNijX8rLSImdQ5HrFZo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}