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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '309ebcf3fbaa1bf49b9e03c2cf69d9b50b42f71b5eea0b7affc604f7474e8f2b' 
  AND token = 'PKHLRxBSJ/lSZlgdgaN8kPf/o2ci4ZtMsOZnyp4gD4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}