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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd8a1d644a584a6348da9a9763c7714246b29f397bec2ebdf369e32ef1c11d17' 
  AND token = 'MVA3QW7gJIgFAWUHM17wtIPzEUn7ZIcyOP+MhLbmqkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}