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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1efe2855095d14b0114258fe8a515cc10325d24c6267d26dbb0ad8a65b498b15' 
  AND token = 'lYNcuU+RnbVJ9T5uB+k7nQjMEfVPvDRAKscQM0ki/84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}