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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc09a78b25ca14447c805bb631a175545d41a69a9b6c321c25f231fad7c301e1' 
  AND token = 'evLuPTgJ2kiJFuyoe8Ob0SOMIOK8gve1zSZwPQuJKf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}