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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cef54a3b2caf616ef433209c8aba072b449a1f2e2b275cd7dce22d2e4e8bc53a' 
  AND token = 'Z3ba0kirOzg3THVTwZfKOmmdCqRJJMzX8bspVtY5rzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}