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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12829c93f476163eb510e6253e0a059f685f03805ff70095ece9620ca8af065' 
  AND token = 'yQcHXbS7Cx978CvsrKBkq0UlRP9xeT3E/kmJat1lx/w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}