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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f6a1749a8f8d6404d997637c459eb3dd8c5dbc35bb358f9bf15fd6f7c6b7fae' 
  AND token = 'NPy6LtXFllCvHjl1V+DbAuqcktyb9k/C34ne6BWqMlg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}