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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b11e750a5f0992e649923b5a6968d5ebf73f8ab24d5aea713094de294a915ad2' 
  AND token = 'X/D2b8WHT+qM+hd5MitYdVtP21mZDwWajqMcl1yWXwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}