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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0721db80418e242d6c1c9de313653f9a0567716603184a45f75afe9e12792986' 
  AND token = 'eUP6AS//39EmNmMhkiz+Ep0mmrBVURk+ORAHYIjpo2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}