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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fce12ab022253e17f2c94ea7e02f1f59bcd7fbb9b28c0cd6b729b494c936f9f' 
  AND token = 'QP3NetOv/jk0v1Zy/OMOaSaZrn6P8PMXcMECycB6J2g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}